Vivas Week 14

1. What type of drug is gliclazide?

Describe the mechanism of action of the sulphonylureas

What are the pharmacokinetics of the sulphonylureas?

2. How are thyroid hormones regulated?

Other than cardiovascular, what are the physiological effects of thyroid hormones?

3. What factors influence glucose homeostasis?

What happens to glucose homeostasis in the absence of insulin?

By what mechanism does glucose cause the release of insulin?

4. Explain the mechanism of action of octreotide

Describe the pharmacokinetics of octreotide

What are some of its clinical uses?

What are its adverse effects?

5. What is the usual dose of dexamethasone for the treatment of croup?

How can dexamethasone be administered?

How does the anti-inflammatory effect of dexamethasone compare to hydrocortisone?

Describe the anti-inflammatory and immunosuppressive effects of glucocorticoids