MCQs Week 6 Loading... 1. Oral amiodarone Has a half-life of 5 daysIncreases the clearance of warfarinIs a structural analogue of oestrogenCan cause photodermatitis Loading... 2. Which of the following is a major manifestation of rheumatic fever? Arthritis involving the small joints of the handsPericarditisErythema nodosumErythema marginatum Loading... 3. Which of the following organs has the greatest blood flow per 100g of tissue? BrainKidneysHeartLiver Loading... 4. Regarding cutaneous circulation The triple response is a normal reaction to injury and is made up of a an initial flare, red reaction then a whealThe triple response persists after a total sympathectomyReactive hyperaemia can only occur in the distal limbsA painful stimuli will cause a generalised cutaneous vasodilation Loading... 5. The most common pathogen in infective endocarditis of native valves is Streptococcus viridansStaphylococcal aureusStaphylococcal epidermisEnterobactericeae Loading... 6. Regarding the nerves of the arm, which of the following statements are INCORRECT? The radial nerve is a terminal branch of the posterior cord of the brachial plexusThe axillary nerve is a terminal branch of the posterior cord of the brachial plexusThe ulnar nerve is a terminal branch of the medial cord of the brachial plexusThe median nerve is a terminal branch of the medial cord of the brachial plexus Loading... 7. In the upper limb The upper trunk of the brachial plexus is prone to injury by forceful depression of the shoulder and results in an Erbs palsy The ulnar nerve is commonly injured in fractures of the surgical neck of the humerusThe musculocutaneous nerve is prone to injury in fractures of the lower third of the humerusThe radial nerve is commonly injured in supracondylar fractures Loading... 8. Which of the following may present as acyanotic congenital heart disease? Ventricular septal defectTetralogy of fallotTransposition of the great arteriesTotal anomalous pulmonary venous connection Loading... 9. Flecainide Is a Class IB anti-arrhythmicIs a potassium channel blockerIs useful in the treatment of ventricular tachyarrhythmias post-MIHas a half-life of 2hrs Loading... 10. Which of the following organs receive the greatest proportion of the cardiac output? BrainKidneysHeart Liver Loading... 11. Regarding verapamil It has no effect on the AV nodeDiarrhoea is a common side effectIt is effective in the treatment of SVTIt is a dihydropyridine calcium channel blocker Loading... 12. Injury to the ulnar nerve will cause paralysis of all of the following EXCEPT Medial half of flexor digitorum profundusFlexor digiti minimi brevisAbductor pollicus longusFlexor carpi ulnaris Loading... 13. A 45yr male presents with an acute coronary syndrome. Which of the following statements regarding the pathogenesis of ACS is true? A severely stenotic pre-existing culprit lesion is necessary Inflammation does not play a partUlceration of an atheromatous plaque may be the causeAtherosclerosis of intramural branches is a common cause Loading... 14. Concerning anti-arrhythmic drugs Quinidine and lignocaine block potassium channelsBeta-adrenergic antagonists should never be used in the treatment of catecholamine-induced arrhythmias associated with phaeochromocytomaAmiodarone lengthens the action potential duration and the QT intervalThe major antiarrhythmic action of verapamil is to slow conduction through the purkinje fibres Loading... 15. Which of the following statements regarding cerebral blood flow is INCORRECT? A rise in venous pressure will cause a decrease in cerebral blood flowAutoregulation will maintain a normal cerebral blood flow at arterial pressures of 70 to 160mmHgWith sympathetic stimulation the the plateau of the pressure-flow curve of cerebral blood flow is extended to the rightGrey matter has a higher average blood flow than white matter Loading... 16. Regarding the brain CO2 transport across the blood-brain barrier is an active processThe GLUT 4 transporter is essential in enhancing the rate of transport of glucose into the CSFThe anterior pituitary lies outside of the blood-brain barrierThe blood-brain barrier can be temporarily disrupted by intravenous injection of hypertonic fluids Loading... 17. Which of the following statements regarding adenosine are INCORRECT? It has a half-life in the blood of 10 secondsIt acts to increase the calcium currentIt directly inhibits the AV node but has lesser effects on the SA nodeIt is less effective in the presence of theophylline Loading... 18. CSF 550ml is produced dailyHas a higher concentration of protein than plasmaIs somewhat more alkaline than plasmaHas a pressure of around 20mmHg when measured in a lumbar tap Loading... 19. The annular ligament of the radius Is covered in synoviumIs attached to the head of the radiusIs attached to the margins of the radial notchClasps the head, neck and shaft of the radius Loading... 20. Blood in which of the following vessels normally has the lowest pO2? Maternal arteryMaternal uterine veinUmbilical veinUmbilical artery Loading... 21. In myocardial infarction Coagulation necrosis is the predominant mechanism of cell deathMyocardial necrosis begins within six minutes of coronary occlusionMyocardial cell death is the sole cause of acute heart failureAround 15% of MIs involved the right coronary artery Loading...
