MCQs Week 19 Loading... 1. Volume of distribution equals Concentration given / Plasma concentrationTotal amount of drug / Plasma concentrationUrinary drug concentration / Plasma concentrationTotal amount of drug / Urine concentration Loading... 2. Which of the following increases the risk of digoxin induced arrhythmias? HyperkalaemiaHypercalcaemiaHypermagnasaemiaHypernatramia Loading... 3. Which of the following NSAIDs is most likely to result in adverse gastrointestinal effects? IndomethacinNaproxenIbuprofenDiclofenac Loading... 4. Biliary excretory function can be tested by Serum ammoniaSerum alkaline phosphataseSerum alanine aminotransferaseSerum creatinine Loading... 5. All of the following increase gastrin secretion EXCEPT CalciumLuminal peptides and amino acidsSecretinAdrenaline Loading... 6. Pancreatic secretion Contains digestive enzymes in alpha granulesSecretes 500ml of pancreatic juice per dayNeutralises gastric acid together with bile and intestinal secretionsIs primarily a reflex in response to the sight and smell of food Loading... 7. A 35yr old man presents with epigastric pain and vomiting. He is found to have a serum lipase of 18000 IU/L. Which of the following may have caused his illness? HyperuricaemiaHyperproteinaemiaHypernatraemiaHypercalcaemia Loading... 8. Regarding gastric secretion Mucin aids autodigestionHydrogen ions move passively from parietal cells into the gastric lumenNormal gastric juice has a pH of approximately 1 when fastingAcid secretion is stimulated by H1 receptor activation Loading... 9. All of the following statements about gastrointestinal hormones are true EXCEPT Gastrin stimulates gastric acid and pepsin secretionCCK stimulates secretion of an enzyme poor alkaline pancreatic juiceGIP stimulates insulin secretionSecretin decreases gastric acid secretion Loading... 10. Regarding ACE inhibitors They prevent the inactivation of bradykininCaptopril is a prodrugThey have no role in treating the normotensive diabetic patientThey are useful antihypertensives in late pregnancy Loading... 11. Gallbladder constriction is primarily controlled by EnterogastroneCCK InsulinSecretin Loading... 12. Which structure does NOT lie in the transverse thoracic plane? Origin of the brachiocephalic trunkJunction between superior and inferior mediastinumSternomanubrial jointTracheal bifurcation Loading... 13. Which one of the following statements concerning a typical intercostal nerve is INCORRECT? It divides into anterior and posterior ramiIt passes in the neurovascular plane between the internal intercostal and innermost intercostal musclesIt has no motor functionIn its course around the body wall the nerve lies below the vein and artery Loading... 14. Which of the following statements regarding hepatitis A are correct? Infection is usually transmitted by the parenteral routeA carrier state is common following initial infectionThe mortality rate is about 1%The incubation period is 2-4weeks Loading...